Chemical formula: C₁₇H₂₀N₂S Molecular mass: 284.419 g/mol PubChem compound: 4926
Do not use during pregnancy, especially during the first three months, unless there are compelling reasons. There is insufficient evidence of the safety of Promazine in human pregnancy nor is there evidence from animal studies that it is free from hazard.
Neonates exposed to antipsychotics (including promazine) during the third trimester of pregnancy are at risk of adverse reactions including extrapyramidal and/or withdrawal symptoms that may vary in severity and duration following delivery. There have been reports of agitation, hypertonia, hypotonia, tremor, somnolence, respiratory distress, or feeding disorder. Consequently, newborns should be monitored carefully.
Promazine should not be used during lactation.
Phenothiazines may impair alertness and induce drowsiness especially at the start of treatment. Alcohol and many other drugs may enhance these effects and impair the ability to drive.
Persons taking these drugs should not drive or operate machinery unless the drug has been shown not to interfere with physical or mental ability.
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