Chemical formula: C₂₁H₂₇NO₃ Molecular mass: 341.444 g/mol PubChem compound: 4932
Propafenone is a class IC anti-arrhythmic agent. It has a stabilising action on myocardial membranes, reduces the fast inward current carried by sodium ions with a reduction in depolarisation rate and prolongs the impulse conduction time in the atrium, AV node and primarily, in the His-Purkinje system.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01BC03 | Propafenone | C Cardiovascular system → C01 Cardiac therapy → C01B Antiarrhythmics, class I and III → C01BC Antiarrhythmics, class Ic |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ARYTHMOL Film coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Propafenone is an active ingredient of these brands:
United States (US)
Albania (AL)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)France (FR)
Germany (DE)
Italy (IT)
Japan (JP)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)Singapore (SG)
South Africa (ZA)
Spain (ES)
Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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