Chemical formula: C₁₇H₂₀N₄O₂ Molecular mass: 312.366 g/mol
Propamidine is a member of the aromatic diamidine group of compounds which possess bacteriostatic properties against a wide range of organisms. These diamidines exert antibacterial action against pyrogenic cocci, antibiotic resistant staphylococci and some Gram-negative bacilli, the activity of the diamidines being retained in the presence of organic matter such as tissue fluids, pus and serum.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D08AC03 | Propamidine | D Dermatologicals → D08 Antiseptics and disinfectants → D08A Antiseptics and disinfectants → D08AC Biguanides and amidines |
| S01AX15 | Propamidine | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AX Other antiinfectives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| BROLENE Eye drops | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Propamidine is an active ingredient of these brands:
Estonia (EE)Ireland (IE)New Zealand (NZ)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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