Propiverine

Chemical formula: C₂₃H₂₉NO₃  Molecular mass: 367.481 g/mol  PubChem compound: 4942

Active ingredient description

Propiverine inhibits calcium influx and modulates intracellular calcium in urinary bladder smooth muscle cells causing musculotropic spasmolysis. Also, it inhibits the efferent connection of the nervus pelvicus due to anticholinergic action.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G04BD06 Propiverine G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BD Urinary antispasmodics
Discover more medicines within G04BD06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DETRUNORM Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 60569-19-9
DrugBank Drug: DB12278
KEGG Drug: D08441
PubChem Compound: 4942
RxNorm Ingredient: 55175
SNOMED-CT Concept: 395997007
Propiverine (substance)
UNII Identifier: 468GE2241L
PROPIVERINE

Medicines

Propiverine is an active ingredient of these brands:

Austria (AT)

Canada (CA)

Croatia (HR)

Estonia (EE)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

  • BUP-4 as PROPIVERINE HYDROCHLORIDE

Singapore (SG)

South Africa (ZA)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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