Propranolol

Chemical formula: C₁₆H₂₁NO₂  Molecular mass: 259.343 g/mol  PubChem compound: 4946

Therapeutic indications

Propranolol is indicated for:

Angina pectoris

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Angina

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypertrophic obstructive cardiomyopathy

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Hypertrophic obstructive cardiomyopathy

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypertension

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Arrhythmias

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Arrhythmia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Migraine

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Migraine

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Essential tremor

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Essential tremor

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Situational and generalised anxiety

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Generalized anxiety disorder

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Thyrotoxicosis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Thyrotoxicosis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Portal hypertension

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Portal hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Arrhythmias

Population group: only children (1 year - 12 years old)

Arrhythmia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Thyrotoxicosis

Population group: only children (1 year - 12 years old)

Thyrotoxicosis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Migraine

Population group: only children (1 year - 12 years old)

Migraine

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Fallot's tetralogy

Population group: only children (1 year - 12 years old)

Tetralogy of Fallot

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Post myocardial infarction (only after 5-21 days)

Population group: only adults (18 years old or older)

Preventive procedure and additionally Myocardial infarction

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Proliferating infantile haemangioma

Population group: only newborns (0 - 40 days old) , infants (40 days - 1 year old)

Propranolol is indicated in the treatment of proliferating infantile haemangioma requiring systemic therapy:

  • Life- or function-threatening haemangioma.
  • Ulcerated haemangioma with pain and/or lack of response to simple wound care measures.
  • Haemangioma with a risk of permanent scars or disfigurement.

It is to be initiated in infants aged 5 weeks to 5 months.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Propranolol is contraindicated in the following cases:

Second degree atrioventricular block

Second degree atrioventricular block

Third degree heart block

Complete atrioventricular block

Sick sinus syndrome

Sick sinus syndrome

Cardiogenic shock

Cardiogenic shock

Metabolic acidosis

Metabolic acidosis

Bradycardia

Bradycardia

Pheochromocytoma

Phaeochromocytoma

Severe peripheral arterial circulatory disturbances

Peripheral arterial occlusive disease

Hypotension (systolic blood pressure <90 mmHg)

Hypotension

Bronchial asthma

Airway hyperreactivity

Bronchospasm

Bronchospasm

Prinzmetal angina

Prinzmetal angina

Decompensated cardiac failure

Decompensated cardiac failure

Hypoglycaemia

Hypoglycaemia

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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