Chemical formula: C₁₆H₂₆N₂O₃ Molecular mass: 294.389 g/mol PubChem compound: 4935
Proxymetacaine is a potent topical anaesthetic of the ester type. The main site of anaesthetic action is the nerve cell membrane where proxymetacaine interferes with the large transient increase in the membrane permeability to sodium ions that is normally produced by a slight depolarisation of the membrane.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| S01HA04 | Proxymetacaine | S Sensory organs → S01 Ophthalmologicals → S01H Local anesthetics → S01HA Local anesthetics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MINIMS PROXYMETACAINE Eye drops, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ALCAINE Eye drops, solution | Medicines and Medical Devices Safety Authority (NZ) | MPI, EU: SmPC |
Proparacaine is an active ingredient of these brands:
United States (US)
Brazil (BR)
Canada (CA)
Cyprus (CY)
Ecuador (EC)Estonia (EE)
Hong Kong (HK)
Lithuania (LT)
New Zealand (NZ)
Poland (PL)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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