Rimegepant

Chemical formula: C₂₈H₂₈F₂N₆O₃  Molecular mass: 534.568 g/mol  PubChem compound: 51049968

Active ingredient description

Rimegepant selectively binds with high affinity to the human calcitonin gene-related peptide (CGRP) receptor and antagonizes CGRP receptor function. The relationship between pharmacodynamic activity and the mechanism(s) by which rimegepant exerts its clinical effects is unknown.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02CD06 N Nervous system → N02 Analgesics → N02C Antimigraine preparations → N02CD Calcitonin gene-related peptide (CGRP) antagonists
Discover more medicines within N02CD06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VYDURA Oral lyophilisate European Medicines Agency (EU) MPI, EU: SmPC
NURTEC ODT Orally disintegrating tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 1289023-67-1
DrugBank Drug: DB12457
PubChem Compound: 51049968
RxNorm Ingredient: 2282307
SNOMED-CT Concept: 860726001
Rimegepant (substance)
UNII Identifier: 997WVV895X
RIMEGEPANT

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