Chemical formula: C₁₉H₁₈ClN₃O₅S Molecular mass: 435.881 g/mol PubChem compound: 9875401
Rivaroxaban is a highly selective direct factor Xa inhibitor with oral bioavailability. Inhibition of factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. Rivaroxaban does not inhibit thrombin (activated factor II) and no effects on platelets have been demonstrated.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B01AF01 | B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AF Direct factor Xa inhibitors | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| XARELTO 15mg Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| XARELTO 2.5mg Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| XARELTO 10mg Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| XARELTO 15mg/20mg Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Rivaroxaban is an active ingredient of these brands:
United States (US)Australia (AU)Austria (AT)Canada (CA)Cyprus (CY)Estonia (EE)Finland (FI)France (FR)Hong Kong (HK)Ireland (IE)Israel (IL)Japan (JP)Mexico (MX)Netherlands (NL)New Zealand (NZ)Nigeria (NG)Romania (RO)Singapore (SG)Spain (ES)Tunisia (TN)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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