Chemical formula: C₁₄H₂₂N₂O₂ Molecular mass: 250.337 g/mol PubChem compound: 77991
Rivastigmine is an acetyl- and butyrylcholinesterase inhibitor of the carbamate type, thought to facilitate cholinergic neurotransmission by slowing the degradation of acetylcholine released by functionally intact cholinergic neurones. Thus, rivastigmine may have an ameliorative effect on cholinergic-mediated cognitive deficits in dementia associated with Alzheimer’s disease and Parkinson’s disease.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06DA03 | Rivastigmine | N Nervous system → N06 Psychoanaleptics → N06D Anti-dementia drugs → N06DA Anticholinesterases |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| EXELON Transdermal patch | European Medicines Agency (EU) | MPI, EU: SmPC | |
| EXELON Hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC |
Rivastigmine is an active ingredient of these brands:
United States (US)
Australia (AU)
Brazil (BR)
Canada (CA)
Ecuador (EC)
France (FR)
Hong Kong (HK)Israel (IL)
Mexico (MX)
New Zealand (NZ)
Poland (PL)Romania (RO)Singapore (SG)
Tunisia (TN)
Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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