Rofecoxib

Chemical formula: C₁₇H₁₄O₄S  Molecular mass: 314.356 g/mol  PubChem compound: 5090

Active ingredient description

Rofecoxib is a nonsteroidal anti-inflammatory drug that exhibits anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of rofecoxib is believed to be due to inhibition of prostaglandin synthesis, via inhibition of cyclooxygenase-2 (COX-2).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
M01AH02 Rofecoxib M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AH Coxibs
Discover more medicines within M01AH02

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 162011-90-7
DrugBank Drug: DB00533
KEGG Drug: D00568
PubChem Compound: 5090
RxNorm Ingredient: 232158
SNOMED-CT Concept: 387008005
Rofecoxib (substance)
UNII Identifier: 0QTW8Z7MCR
ROFECOXIB
 
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