Chemical formula: C₂₆H₂₆ClN₃ Molecular mass: 415.97 g/mol PubChem compound: 133017
Rupatadine is a second-generation antihistamine, long-acting histamine antagonist, with selective peripheral H1-receptor antagonist activity. Some of the metabolites (desloratadine and its hydroxylated metabolites) retain an antihistaminic activity and may partially contribute to the overall efficacy of the drug.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R06AX28 | Rupatadine | R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AX Other antihistamines for systemic use |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| RUPATADINE Oral solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| RUPATADINE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Rupatadine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Canada (CA)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
France (FR)
Ireland (IE)
Israel (IL)
Italy (IT)Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)Romania (RO)
Singapore (SG)
Spain (ES)
Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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