Sacubitril

Chemical formula: C₂₄H₂₉NO₅ Molecular mass: 411.498 g/mol PubChem compound: 9811834

Active ingredient description

Sacubitril is a prodrug and its active metabolite, LBQ657, inhibits neprilysin (neutral endopeptidase; NEP). The complementary cardiovascular benefits in heart failure patients are attributed to the enhancement of peptides that are degraded by neprilysin, such as natriuretic peptides (NP), by LBQ657.

Medicines

Sacubitril is an active ingredient of these brands:

United States (US)

(combination) ENTRESTO

Australia (AU)

(combination) ENTRESTO

Austria (AT)

(combination) ENTRESTO
(combination) NEPARVIS

Brazil (BR)

(combination) ENTRESTO

Canada (CA)

(combination) ENTRESTO

Cyprus (CY)

(combination) ENTRESTO

Ecuador (EC)

(combination) ENTRESTO

Estonia (EE)

(combination) ENTRESTO
(combination) NEPARVIS

Finland (FI)

(combination) ENTRESTO

France (FR)

(combination) ENTRESTO

Hong Kong (HK)

(combination) ENTRESTO

Ireland (IE)

(combination) ENTRESTO
(combination) NEPARVIS

Israel (IL)

(combination) ENTRESTO

Japan (JP)

(combination) ENTRESTO

Lithuania (LT)

(combination) ENTRESTO
(combination) NEPARVIS

Netherlands (NL)

(combination) ENTRESTO

New Zealand (NZ)

(combination) ENTRESTO

Poland (PL)

(combination) ENTRESTO
(combination) NEPARVIS

Romania (RO)

(combination) ENTRESTO

Singapore (SG)

(combination) ENTRESTO

South Africa (ZA)

(combination) ENTRESTO
(combination) VYMADA

Spain (ES)

(combination) ENTRESTO
(combination) NEPARVIS

Tunisia (TN)

(combination) ENTRESTO

Turkey (TR)

(combination) NEPRILEX as SACUBITRIL SODIUM
(combination) ONEPTUS

United Kingdom (UK)

(combination) ENTRESTO

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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