Salicylic acid

Chemical formula: C₇H₆O₃  Molecular mass: 138.121 g/mol  PubChem compound: 338

Interactions

Salicylic acid interacts in the following cases:

Sulfonamides, urea derivatives

Systemically absorbed salicylic acid may enhance the hypoglycemic activity of the sulfonamides, urea derivatives.

Acetazolamide

Salicylic acid administered at high doses increases the activity of acetazolamide.

Methotrexate

Systemically absorbed salicylic acid may increase the toxicity of methotrexate.

Pregnancy

Whilst there are no known contra-indications to use of salicylic acid during pregnancy, the safety has not been established. Salicylic acid should therefore be used with caution or following professional advice.

Nursing mothers

Whilst there are no known contra-indications to use of salicylic acid during actation, the safety has not been established. Salicylic acid should therefore be used with caution or following professional advice.

Effects on ability to drive and use machines

None known.

Adverse reactions


Undesirable effects are listed by MedDRA System Organ Classes.

Assessment of undesirable effects is based on the following frequency groupings: Very common ≥1/10, Common ≥1/100 to <1/10, Uncommon ≥1/1,000 to <1/100, Rare ≥1/10,000 to <1/1,000, Very rare <1/10,000, Not known cannot be estimated from the available data.

Skin and subcutaneous tissue disorders

Not known: skin irritation*

Injury, poisoning and procedural complications

Not known: salicylism (including tinnitus)

* A localised irritant reaction may occur if salicylic acid is applied to normal skin surrounding the wart. This may normally be controlled by temporarily discontinuing the use of salicylic acid and by being careful to apply the solution only to the wart itself when treatment is resumed.

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