Satraplatin

Molecular mass: 500.283 g/mol  PubChem compound: 123974

Active ingredient description

Satraplatin is a cytotoxic agent. The primary cytotoxic mechanism of satraplatin is similar to that of other platinum compounds including cisplatin, carboplatin and oxaliplatin, and is based on the formation of DNA adducts. Platinum-DNA adducts, which are formed following uptake of the drug into the nucleus of the cell, activate several cellular processes that mediate the cytotoxicity of these drugs. These processes include the signalling of DNA damage, cell cycle checkpoints and arrest, DNA repair and cell death.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01XA04 Satraplatin L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XA Platinum compounds
Discover more medicines within L01XA04

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 129580-63-8
DrugBank Drug: DB04996
PubChem Compound: 123974
RxNorm Ingredient: 1733681
SNOMED-CT Concept: 428317007
Satraplatin (substance)
UNII Identifier: 8D7B37T28G
SATRAPLATIN

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