Chemical formula: C₁₇H₁₇Cl₂N Molecular mass: 306.23 g/mol PubChem compound: 68617
Sertraline is a potent and specific inhibitor of neuronal serotonin (5-HT) uptake in vitro, which results in the potentiation of the effects of 5-HT in animals. It has only very weak effects on norepinephrine and dopamine neuronal reuptake.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06AB06 | Sertraline | N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AB Selective serotonin reuptake inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| SERTRALINE Film coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ZOLOFT Film-coated tablet / Oral solution | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Sertraline is an active ingredient of these brands:
United States (US)
Brazil (BR)
Canada (CA)
Croatia (HR)Ecuador (EC)Estonia (EE)Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)Japan (JP)
Lithuania (LT)
Mexico (MX)
Netherlands (NL)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)South Africa (ZA)
Spain (ES)Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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