Sirolimus Other names: Rapamycin Sirolimus

Chemical formula: C₅₁H₇₉NO₁₃  Molecular mass: 914.187 g/mol  PubChem compound: 5284616

Therapeutic indications

Sirolimus is indicated for:

Prophylaxis of renal transplant rejection

Population group: only adults (18 years old or older)

Sirolimus is indicated for the prophylaxis of organ rejection in adult patients at low to moderate immunological risk receiving a renal transplant. It is recommended that sirolimus be used initially in combination with ciclosporin microemulsion and corticosteroids for 2 to 3 months. Sirolimus may be continued as maintenance therapy with corticosteroids only if ciclosporin microemulsion can be progressively discontinued.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Sporadic lymphangioleiomyomatosis

Population group: only adults (18 years old or older)

Sirolimus is indicated for the treatment of patients with sporadic lymphangioleiomyomatosis with moderate lung disease or declining lung function.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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