Chemical formula: C₈H₁₆O₂ Molecular mass: 144.211 g/mol PubChem compound: 3121
Valproic acid is anti-convulsant. The most likely mode of action for valproate is potentiation of the inhibitory action of gamma amino butyric acid (GABA) through an action on the further synthesis or further metabolism of GABA.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N03AG01 | Valproic acid | N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AG Fatty acid derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| EPILIM Powder and solvent for solution for injection / infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DEPAKOTE Delayed-release tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| DEPAKOTE SPRINKLES Capsule | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| EPILIM CHRONOSPHERE Modified release granules | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Valproic acid is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)
Brazil (BR)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Italy (IT)
Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)Spain (ES)
Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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