Sofosbuvir

Chemical formula: C₂₂H₂₉FN₃O₉P Molecular mass: 529.458 g/mol PubChem compound: 45375808

Therapeutic indications

Sofosbuvir is indicated for:

Chronic hepatitis C (CHC)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Sofosbuvir is indicated in combination with other medicinal products for the treatment of chronic hepatitis C (CHC) in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

400 mg once daily

For patients weighting <17 150 mg once daily, for patients weighting 17 to <35 kg 200 mg once daily and for patients weighting ≥35 kg 400 mg once daily

Contraindications

Sofosbuvir is contraindicated in the following cases:

Carbamazepine, phenobarbital, phenytoin, rifampicin, St. John's wort

at least one of

Carbamazepine
Phenobarbital
Phenytoin
Rifampicin
Hypericum perforatum (St John's Wort)

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