Chemical formula: C₈H₁₅N₃O₇ Molecular mass: 265.221 g/mol PubChem compound: 29327
Streptozocin interacts in the following cases:
There are no data from the use of streptozocin in pregnant women. Animal studies have shown reproductive toxicity.
Streptozocin is not recommended during pregnancy.
Streptozocin should be used in pregnancy only if the potential benefit to the mother outweighs the potential risks to the fetus.
It is unknown whether streptozocin and/or its metabolites are excreted in human milk. A risk to the newborns/infants cannot be excluded. Therefore, breast-feeding should be discontinued during treatment with streptozocin.
Streptozocin is not recommended in women of childbearing potential not using contraception. An effective method of contraception should be used during treatment. A period of contraception post-treatment of 90 days for men, and 30 days for women should be applied.
There are no data on fertility in humans. In non-clinical studies, streptozocin adversely affected fertility when administered to male and female rats. Therefore, men being treated with streptozocin are advised not to attempt to father a child for 90 days after treatment and to seek advice on conservation of sperm prior to treatment.
Streptozocin may cause confusion, lethargy or depression.
Patients should be advised not to drive or use machines if they experience any adverse reaction that may affect their ability to perform these tasks.
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