Sulfur hexafluoride

Chemical formula: F₆S  Molecular mass: 146.05 g/mol  PubChem compound: 17358

Therapeutic indications

Sulfur hexafluoride is indicated for:

Contrast echocardiography

Population group: only adults (18 years old or older)

Sulfur hexafluoride is a transpulmonary echocardiographic contrast agent for use in adult patients with suspected or established cardiovascular disease to provide opacification of cardiac chambers and enhance left ventricular endocardial border delineation.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Doppler ultrasonography of blood vessel

Population group: only adults (18 years old or older)

Sulphur hexafluoride increases the accuracy in detection or exclusion of abnormalities in cerebral arteries and extracranial carotid or peripheral arteries in adult patients by improving the Doppler signal to noise ratio.

Sulphur hexafluoride increases the quality of the Doppler flow image and the duration of clinically-useful signal enhancement in portal vein assessment in adult patients.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ultrasonography of excretory urinary tract

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Sulphur hexafluoride is indicated for use in ultrasonography of the excretory tract in paediatric patients from newborn to 18 years to detect vesicoureteral reflux.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Doppler sonography

Population group: only adults (18 years old or older)

Sulphur hexafluoride improves display of the vascularity of liver and breast lesions during Doppler sonography in adult patients leading to more specific lesion characterisation.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Sulfur hexafluoride is contraindicated in the following cases:

Right-to-left shunts

Right to left cardiac shunt

Severe pulmonary hypertension (pulmonary artery pressure >90 mmHg)

Severe pulmonary hypertension

Adult respiratory distress syndrome

Adult respiratory distress syndrome

Uncontrolled systemic hypertension

Hypertensive crisis

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