Tasimelteon

Chemical formula: C₁₅H₁₉NO₂  Molecular mass: 245.322 g/mol  PubChem compound: 10220503

Active ingredient description

Tasimelteon is a circadian regulator that resets the master body clock in the suprachiasmatic nucleus (SCN). Tasimelteon acts as a Dual Melatonin Receptor Agonist (DMRA) with selective agonist activity at the MT1 and MT2 receptors. These receptors are thought to be involved in the control of circadian rhythms. It is indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (Non-24) in totally blind adults.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05CH03 N Nervous system → N05 Psycholeptics → N05C Hypnotics and sedatives → N05CH Melatonin receptor agonists
Discover more medicines within N05CH03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
HETLIOZ Capsule FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 609799-22-6
DrugBank Drug: DB09071
KEGG Drug: D09388
PubChem Compound: 10220503
RxNorm Ingredient: 1490468
SNOMED-CT Concept: 702394009
Tasimelteon (substance)
UNII Identifier: SHS4PU80D9
TASIMELTEON

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