Teduglutide

Chemical formula: C₁₆₄H₂₅₂N₄₄O₅₅S  Molecular mass: 3,750.803 g/mol 

Active ingredient description

Teduglutide is an analogue of GLP-2. The naturally occurring human glucagon-like peptide-2 (GLP-2) is a peptide secreted by L cells of the intestine which is known to increase intestinal and portal blood flow, inhibit gastric acid secretion, and decrease intestinal motility. In several nonclinical studies, teduglutide has been shown to preserve mucosal integrity by promoting repair and normal growth of the intestine through an increase of villus height and crypt depth.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A16AX08 Teduglutide A Alimentary tract and metabolism → A16 Other alimentary tract and metabolism products → A16A Other alimentary tract and metabolism products → A16AX Various alimentary tract and metabolism products
Discover more medicines within A16AX08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
REVESTIVE Powder and solvent for solution for injection European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

CAS Substance: 197922-42-2
DrugBank Drug: DB08900
KEGG Drug: D06053
RxNorm Ingredient: 1364468
SNOMED-CT Concept: 710807004
Teduglutide (substance)
UNII Identifier: 7M19191IKG
TEDUGLUTIDE

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