Chemical formula: C₄₃H₆₅N₅O₁₀ Molecular mass: 812.018 g/mol PubChem compound: 3002190
Telithromycin interacts in the following cases:
There are no adequate data from the use of telithromycin in pregnant women. Studies in animals have shown reproductive toxicity. The potential risk for humans is unknown.
Telithromycin should not be used during pregnancy unless clearly necessary.
Telithromycin is excreted in the milk of lactating animals, at concentrations about 5 times those of maternal plasma. Corresponding data for humans is not available.
Telithromycin should not be used by breastfeeding women.
In studies with rats a reduction in fertility indices was observed at parentally toxic doses.
Telithromycin may cause adverse reactions such as visual disturbances, confusion or hallucination which may reduce the capacity for the completion of certain tasks. In addition, rare cases of transient loss of consciousness, which may be preceded by vagal symptoms, have been reported. Because of potential visual difficulties, loss of consciousness, confusion or hallucination, patients should attempt to minimize activities such as driving a motor vehicle, operating heavy machinery or engaging in other hazardous activities during treatment with telithromycin. If patients experience visual disorders, loss of consciousness, confusion or hallucination while taking telithromycin, patients should not drive a motor vehicle, operate heavy machinery or engage in other hazardous activities.
Patients should be informed that these adverse reactions may occur as early as after the first dose of medicinal product. Patients should be cautioned about the potential effects of these events on the ability to drive or operate machinery.
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