Temgicoluril Other names: Tetramethylglycoluril

Chemical formula: C₈H₁₄N₄O₂  Molecular mass: 198.226 g/mol 

Active ingredient description

Temgicoluril has an effect on the structure of limbic–reticular activity, particularly on hypothalamus emotional zone, as well as on all several basic neuromediator systems – γ aminobutyric acid (GABA), choline, serotonin, and adrenergic activity. It decreases brain norepinephrine levels and increases brain serotonin levels without modulating dopaminergic systems or cholinergic systems. Temgicoluril purportedly has anti-anxiety (anxiolytic) properties. It is also used to aid smoking cessation. In addition, temgicoluril may be useful in the treatment of adult attention-deficit/hyperactivity disorder (ADHD) symptoms.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N06BX21 N Nervous system → N06 Psychoanaleptics → N06B Psychostimulants, agents used for ADHD and nootropics → N06BX Other psychostimulants and nootropics
Discover more medicines within N06BX21

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 10095-06-4
DrugBank Drug: DB13522
UNII Identifier: 55FE6NPG89
TEMGICOLURIL

Medicines

Temgicoluril is an active ingredient of these brands:

Estonia (EE)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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