Temozolomide

Chemical formula: C₆H₆N₆O₂  Molecular mass: 194.151 g/mol  PubChem compound: 5394

Therapeutic indications

Temozolomide is indicated for:

Glioblastoma multiforme

Population group: only adults (18 years old or older)

Temozolomide is indicated for the treatment of adult patients with newly-diagnosed glioblastoma multiforme concomitantly with radiotherapy (RT) and subsequently as monotherapy treatment.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Malignant glioma

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Temozolomide is indicated for the treatment of children from the age of three years, adolescents and adult patients with malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma, showing recurrence or progression after standard therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Temozolomide is contraindicated in the following cases:

Severe myelosuppression

Myelosuppression

Hypersensitivity to dacarbazine (DTIC)

Dacarbazine allergy

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