Tetrabenazine Other names: Tetrabenzaine

Chemical formula: C₁₉H₂₇NO₃  Molecular mass: 317.423 g/mol  PubChem compound: 6018

Therapeutic indications

Tetrabenazine is indicated for:

Huntington's chorea

Population group: only adults (18 years old or older)

Huntington's chorea

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Tardive dyskinesia

Population group: only adults (18 - 65 years old)

Tetrabenazine is indicated for the treatment of moderate to severe tardive dyskinesia, which is disabling and/or socially embarrassing. The condition should be persistent despite withdrawal of antipsychotic therapy, or in cases where withdrawal of antipsychotic medication is not a realistic option; also where the condition persists despite reduction in dosage of antipsychotic medication or switching to atypical antipsychotic medication.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Organic central nervous system movement disorders

Population group: only adults (18 - 65 years old)

Movement disorder

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Tetrabenazine is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Hepatic insufficiency

Hepatic insufficiency

Actively suicidal patients

Suicidal intent

Patients with poorly controlled clinical depression

Depressive disorder

Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs)

Parkinsonism and hypokinetic-rigid syndrome

Parkinsonism

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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