Chemical formula: O₃S₂-₂ Molecular mass: 114.144 g/mol PubChem compound: 24478
Thiosulfate is indicated for:
Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Sodium thiosulfate is indicated for the prevention of ototoxicity induced by cisplatin chemotherapy in patients 1 month to <18 years of age with localised, non-metastatic, solid tumours.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Population group: only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old) , adults (18 years old or older)
Sodium thiosulfate is indicated for sequential use with hydroxocobalamin or sodium nitrite for the treatment of acute cyanide poisoning that is judged to be life-threatening.
When the diagnosis of cyanide poisoning is uncertain, the potentially life-threatening risks associated with sodium thiosulfate should be carefully weighed against the potential benefits, especially if the patient is not in extremis.
Sodium thiosulfate is to be administered together with appropriate decontamination and supportive measures.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Thiosulfate is contraindicated in the following cases:
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