Tiagabine

Chemical formula: C₂₀H₂₅NO₂S₂  Molecular mass: 375.548 g/mol  PubChem compound: 60648

Active ingredient description

Tiagabine is an anti-epileptic drug. Tiagabine is a potent and selective inhibitor of both neuronal and glial GABA uptake, which results in an increase in GABAergic medicated inhibition in the brain.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N03AG06 Tiagabine N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AG Fatty acid derivatives
Discover more medicines within N03AG06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
GABITRIL Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 115103-54-3
DrugBank Drug: DB00906
KEGG Drug: D08588
PubChem Compound: 60648
RxNorm Ingredient: 31914
SNOMED-CT Concept: 372485004
Tiagabine (substance)
UNII Identifier: Z80I64HMNP
TIAGABINE

Medicines

Tiagabine is an active ingredient of these brands:

United States (US)

  • GABITRIL as Tiagabine hydrochloride monohydrate

Australia (AU)

  • GABITRIL as Tiagabine hydrochloride monohydrate

France (FR)

  • GABITRIL as Tiagabine hydrochloride monohydrate

Ireland (IE)

  • GABITRIL as Tiagabine hydrochloride monohydrate

Lithuania (LT)

  • GABITRIL as Tiagabine hydrochloride monohydrate

Poland (PL)

  • GABITRIL as Tiagabine hydrochloride monohydrate

Spain (ES)

  • GABITRIL as Tiagabine hydrochloride monohydrate

United Kingdom (UK)

  • GABITRIL as Tiagabine hydrochloride monohydrate

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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