Tobramycin
Active ingredient description
Tobramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. It acts primarily by disrupting protein synthesis leading to altered cell membrane permeability, progressive disruption of the cell envelope and eventual cell death. It is bactericidal at concentrations equal to or slightly greater than inhibitory concentrations.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Medicines
Tobramycin is the active ingredient of these drugs:
Ecuador
United States
Austria Brazil Estonia Ireland Italy
Ecuador
Cyprus
Hong Kong
United States
Ecuador
United Kingdom
South Africa
France
Italy
Estonia Netherlands
Hong Kong
Hong Kong
Ecuador
Ecuador
Hong Kong
Australia Austria Brazil Canada Cyprus
Singapore
France South Africa Spain
Brazil
Tunisia
Brazil
Ecuador
Hong Kong
South Africa
Ecuador
Brazil
Brazil
Brazil
Austria
Brazil Ecuador
Australia Austria Brazil Canada Cyprus
Poland Spain
Ecuador Lithuania
Poland
Estonia
Hong Kong
Ecuador
Ireland United Kingdom
Spain
Austria Estonia Lithuania Netherlands Spain
Ecuador
Brazil Ecuador
Tobramycin is also found within below combination drugs:
ACROTERF PLUS , BRADEXA , BRAZOFLAMIN , DEXAGEN T , DEXATOBRIN , DEXTO , LOFOTO , MYBRACIN , NEBCIN CO , OCTUDEX , OFTOL PLUS , POENTOBRAL PLUS , STEDEX-T , TOBADEXA , TOBESON , TOBRACIN D , TOBRACORT , TOBRADEX , TOBRAL D , TOBRAOFTAL D , TOBRASONE , TOBRICH , TOBROSOPT-DEX , TODEXAL , TRAZIDEX , TRAZINAC , XOLOF-D , ZYLET , ZYLETH
Structural formula
Chemical formula: C₁₈H₃₇N₅O₉
Molecular mass: 467.515 g/mol