Tradipitant
Chemical formula: C₂₈H₁₆ClF₆N₅O Molecular mass: 587.095 g/mol PubChem compound: 9916461
Active ingredient description
Tradipitant is a selective, high-affinity antagonist of human substance P/neurokinin-1 (NK-1) receptors. Tradipitant does not have affinity for NK2 and NK3, serotonin (5-HT3), dopamine (D2), cholinergic, or histamine (H1) receptors. The exact mechanism by which tradipitant exerts its therapeutic effect is not fully established.
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| NEREUS Capsule | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
Medicines
Tradipitant is an active ingredient of these brands:
United States (US)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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