Triamterene

Chemical formula: C₁₂H₁₁N₇  Molecular mass: 253.263 g/mol  PubChem compound: 5546

Therapeutic indications

Triamterene is indicated for:

Edema

Population group: only adults (18 years old or older)

Triamterene is indicated in the treatment of edema associated with congestive heart failure, cirrhosis of the liver and the nephrotic syndrome.

Triamterene may be used alone or with other diuretics, either for its added diuretic effect or its potassium-sparing potential. It also promotes increased diuresis when patients prove resistant or only partially responsive to thiazides or other diuretics because of secondary hyperaldosteronism.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Steroid-induced edema

Population group: only adults (18 years old or older)

Triamterene may be used alone or with other diuretics, either for its added diuretic effect or its potassium-sparing potential. It also promotes increased diuresis when patients prove resistant or only partially responsive to thiazides or other diuretics because of secondary hyperaldosteronism.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Idiopathic edema

Population group: only adults (18 years old or older)

Idiopathic edema

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Edema due to secondary hyperaldosteronism

Population group: only adults (18 years old or older)

Interstitial edema and additionally Secondary aldosteronism

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Triamterene is contraindicated in the following cases:

Lactation

Lactation

Anuria

Anuria

Severe renal impairment

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe hepatic disease

Hepatic failure stage IV

Pre-existing elevated serum potassium

at least one of
Hyperkalemia
Raised serum potassium level

Potassium

Potassium

Potassium-sparing agents

Potassium-sparing agents

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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