Triclosan

Chemical formula: C₁₂H₇Cl₃O₂  Molecular mass: 289.542 g/mol  PubChem compound: 5564

Pharmacodynamic properties

Triclosan is a chlorinated bisphenol antiseptic.

Triclosan is effective against Gram-positive and most Gram-negative bacteria.

Triclosan has proven efficacy against Stapylococcus aureus, the principal causative organism in infected eczemas.

Pharmacokinetic properties

Studies of triclosan after cutaneous use showed minimal absorption.

Preclinical safety data

Triclosan is not reported to be genotoxic in bacterial and mammalian test systems.

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