Tropisetron Other names: Tropisetron hydrochloride

Chemical formula: C₁₇H₂₀N₂O₂  Molecular mass: 284.353 g/mol  PubChem compound: 656665

Active ingredient description

Tropisetron is a highly potent and selective competitive antagonist of the 5-HT3 receptor. Tropisetron selectively blocks the excitation of the presynaptic 5-HT3 receptors of the peripheral neurons in this reflex, and may exert additional direct actions within the CNS on 5-HT3 receptors mediating the actions of vagal input to the area postrema.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A04AA03 Tropisetron A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AA Serotonin (5HT3) antagonists
Discover more medicines within A04AA03

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 89565-68-4
DrugBank Drug: DB11699
PubChem Compound: 656665
RxNorm Ingredient: 27392
SNOMED-CT Concept: 395917006
Tropisetron (substance)
UNII Identifier: 6I819NIK1W
TROPISETRON

Medicines

Tropisetron is an active ingredient of these brands:

Austria (AT)

  • NAVOBAN as TROPISETRON HYDROCHLORIDE

Hong Kong (HK)

South Africa (ZA)

  • NAVOBAN as TROPISETRON HYDROCHLORIDE

Turkey (TR)

  • NAVOBAN as TROPISETRON HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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