Urofollitropin

Chemical formula: C₄₂H₆₅N₁₁O₁₂S₂  Molecular mass: 979.426 g/mol 

Therapeutic indications

Urofollitropin is indicated for:

Female infertility in anovulation

Population group: women, only adults (18 - 65 years old)

Urofollitropin is indicated for the treatment of female infertility in anovulation (including polycystic ovarian disease (PCOD)) in women who have been unresponsive to treatment with clomiphene citrate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Controlled ovarian hyperstimulation

Population group: women, only adults (18 - 65 years old)

Urofollitropin is indicated for the treatment of female infertility in controlled ovarian hyperstimulation to induce the development of multiple follicles for assisted reproductive technologies (ART) (e.g. in vitro fertilisation/embryo transfer (IVF/ET), gamete intra-fallopian transfer (GIFT) and intracytoplasmic sperm injection (ICSI)).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Urofollitropin is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Primary ovarian failure

Primary ovarian failure

Fibroid tumours of the uterus

Uterine leiomyoma

Ovarian cysts, enlarged ovaries

at least one of
Ovarian cyst and additionally not Polycystic ovary

Ovarian enlargement

Gynaecological haemorrhage

at least one of
Observations of vaginal bleeding
Hematometra

Ovarian, uterine or mammary carcinoma

at least one of
Malignant epithelial tumor of ovary
Carcinoma of corpus uteri
CA - Carcinoma of breast

Tumours of the pituitary or hypothalamic glands

at least one of
Neoplasm of pituitary gland
Tumor of hypothalamus

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2016: BRAVELLE Powder and solvent for solution for injection
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