Veligrotug's mechanism of action in patients with thyroid eye disease has not been fully characterized. Veligrotug is a humanized IgG1 monoclonal antibody that binds to IGF-1R and inhibits IGF-1R signaling by blocking ligand-induced receptor autophosphorylation.
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| LUMVOA Solution for injection | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
Veligrotug is an active ingredient of these brands:
United States (US)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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