Verteporfin C₁₆₄H₁₆₈N₁₆O₃₂

Active ingredient description

Verteporfin, also referred to as benzoporphyrin derivative monoacids (BPD-MA) consists of a 1:1 mixture of the equally active regioisomers BPD-MAC and BPD-MAD. It produces cytotoxic agents only when activated by light in the presence of oxygen. The selectivity of PDT using verteporfin is based, in addition to the localised light exposure, on selective and rapid uptake and retention of verteporfin by rapidly proliferating cells including the endothelium of choroidal neovasculature.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
S Sensory organs → S01 Ophthalmologicals → S01L Ocular vascular disorder agents → S01LA Antineovascularisation agents
Discover more medicines within S01LA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Information Source
Document Type
European Medicines Agency (EU)
Summary of Product Characteristics (SPC)

Chemical formula: C₁₆₄H₁₆₈N₁₆O₃₂
Molecular mass: 718.794 g/mol

External identifiers

CAS Substance: 129497-78-5
DrugBank Drug: DB00460
KEGG Drug: D01162
PubChem Compound: 5362420
RxNorm Ingredient: 118886
SNOMED-CT Concept: 327046007
Verteporfin (substance)
SNOMED-CT Concept: 387059006
Verteporfin (substance)
UNII Identifier: 0X9PA28K43


Verteporfin is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

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