Chemical formula: C₆H₁₁NO₂  Molecular mass: 129.157 g/mol  PubChem compound: 5665

Active ingredient description

Vigabatrin is a selective irreversible inhibitor of GABA transaminase, the enzyme responsible for the breakdown of GABA (gamma aminobutyric acid). Vigabatrin increases the concentration of GABA, the major inhibitory neurotransmitter in the brain.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AG Fatty acid derivatives
Discover more medicines within N03AG04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Information Source
Document Type
European Medicines Agency (EU)
Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 60643-86-9
CAS Substance: 68506-86-5
DrugBank Drug: DB01080
KEGG Drug: D00535
PubChem Compound: 5665
RxNorm Ingredient: 14851
SNOMED-CT Concept: 310283001
Vigabatrin (substance)
UNII Identifier: GR120KRT6K


Vigabatrin is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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