Vilanterol

Chemical formula: C₂₄H₃₃Cl₂NO₅  Molecular mass: 486.43 g/mol  PubChem compound: 10184665

Active ingredient description

Vilanterol is a selective long-acting, beta2-adrenergic agonist (LABA). The pharmacologic effects of beta2-adrenoceptor agonist active substances, including vilanterol, are at least in part attributable to stimulation of intracellular adenylate cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels cause relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R03AK10 Vilanterol and fluticasone furoate R Respiratory system → R03 Drugs for obstructive airway diseases → R03A Adrenergics, inhalants → R03AK Adrenergics and other drugs for obstructive airway diseases
Discover more medicines within R03AK10
R03AL03 Vilanterol and umeclidinium bromide R Respiratory system → R03 Drugs for obstructive airway diseases → R03A Adrenergics, inhalants → R03AL Adrenergics in combination with anticholinergics
Discover more medicines within R03AL03

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 503068-34-6
DrugBank Drug: DB09082
KEGG Drug: D09696
PubChem Compound: 10184665
RxNorm Ingredient: 1424884
SNOMED-CT Concept: 702408004
Vilanterol (substance)
UNII Identifier: 028LZY775B
VILANTEROL

Medicines

Vilanterol is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

  • (combination) ANORO ELLIPTA as VILANTEROL TRIFENATATE
  • (combination) RELVAR as VILANTEROL TRIFENATATE

Ecuador (EC)

  • (combination) ANORO ELLIPTA as VILANTEROL TRIFENATATE
  • (combination) RELVAR as VILANTEROL TRIFENATATE

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

  • (combination) ANORO
  • (combination) RELVAR as VILANTEROL TRIFENATATE

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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