Vinorelbine

Chemical formula: C₄₅H₅₄N₄O₈  Molecular mass: 778.947 g/mol  PubChem compound: 44424639

Active ingredient description

Vinorelbine is an antineoplastic drug of the vinca alkaloid family but unlike all the other vinca alkaloids. Vinorelbine inhibits tubulin polymerization and blocks mitosis at G2-M, causing cell death in interphase or at the following mitosis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01CA04 Vinorelbine L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01C Plant alkaloids and other natural products → L01CA Vinca alkaloids and analogues
Discover more medicines within L01CA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VINORELBINE Soft capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
VINORELBINE Concentrate for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 71486-22-1
DrugBank Drug: DB00361
KEGG Drug: D08680
PubChem Compound: 44424639
RxNorm Ingredient: 39541
SNOMED-CT Concept: 372541004
Vinorelbine (substance)
UNII Identifier: Q6C979R91Y
VINORELBINE

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