Vitamin B12a Other names: Hydroxocobalamin Hydroxycobalamin

Chemical formula: C₆₂H₈₉CoN₁₃O₁₅P  Molecular mass: 1,346.355 g/mol  PubChem compound: 70678542

Active ingredient description

Hydroxocobalamin is a cyanide antidote. Its action in the treatment of cyanide poisoning is based on its ability to bind cyanide ions. Each hydroxocobalamin molecule can bind one cyanide ion by substituting it for the hydroxo ligand linked to the trivalent cobalt ion, to form cyanocobalamin, which is then excreted in the urine.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B03BA03 Hydroxocobalamin B Blood and blood forming organs → B03 Antianemic preparations → B03B Vitamin B12 and folic acid → B03BA Vitamin B12 (cyanocobalamin and analogues)
Discover more medicines within B03BA03
V03AB33 Hydroxocobalamin V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AB Antidotes
Discover more medicines within V03AB33

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CYANOKIT Powder for solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 13422-51-0
DrugBank Drug: DB00200
KEGG Drug: D01027
PubChem Compound: 70678542
RxNorm Ingredient: 5514
SNOMED-CT Concept: 409258004
Hydroxocobalamin (substance)
UNII Identifier: Q40X8H422O
HYDROXOCOBALAMIN

Medicines

Vitamin B12a is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Croatia (HR)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

Poland (PL)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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