Xipamide

Chemical formula: C₁₅H₁₅ClN₂O₄S  Molecular mass: 354.81 g/mol 

Active ingredient description

Xipamide is an anti-hypertensive diuretic which can be characterised pharmacologically neither as a thiazide nor as a specific loop diuretic. Although structurally similar to chlorthalidone, it has a markedly different pharmacological profile with its main diuretic effect exerted at the distal section of the nephron.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C03BA10 Xipamide C Cardiovascular system → C03 Diuretics → C03B Low-ceiling diuretics, excl. thiazides → C03BA Sulfonamides, plain
Discover more medicines within C03BA10

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DIUREXAN Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 14293-44-8
DrugBank Drug: DB13803
RxNorm Ingredient: 11371
SNOMED-CT Concept: 395923001
Xipamide (substance)
UNII Identifier: 4S9EY0NUEC
XIPAMIDE

Medicines

Xipamide is an active ingredient of these brands:

Austria (AT)

Germany (DE)

South Africa (ZA)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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