Ziconotide

Chemical formula: C₁₀₂H₁₇₂N₃₆O₃₂S₇  Molecular mass: 2,639.14 g/mol 

Active ingredient description

Ziconotide is a synthetic analogue of a ω-conopeptide, MVIIA, found in the venom of the Conus magus marine snail. It is an N-type calcium channel blocker (NCCB). In binding to these neuronal NCCs ziconotide inhibits the voltage sensitive calcium current into primary nociceptive afferents terminating in the superficial layers of the dorsal horn of the spinal cord.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02BG08 Ziconotide N Nervous system → N02 Analgesics → N02B Other analgesics and antipyretics → N02BG Other analgesics and antipyretics
Discover more medicines within N02BG08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PRIALT Solution for infusion European Medicines Agency (EU) MPI, EU: SmPC

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 107452-89-1
DrugBank Drug: DB06283
KEGG Drug: D06363
RxNorm Ingredient: 68503
SNOMED-CT Concept: 416512006
Ziconotide (substance)
UNII Identifier: 7I64C51O16
ZICONOTIDE

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