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ATC Group: A02A Antacids

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A02
Drugs for acid related disorders
3
A02A
Antacids

Contents

Code
Title
A02AA
Magnesium compounds
A02AB
Aluminium compounds
A02AC
Calcium compounds
A02AD
Combinations and complexes of aluminium, calcium and magnesium compounds
A02AF
Antacids with antiflatulents
A02AG
Antacids with antispasmodics
A02AH
Antacids with sodium bicarbonate
A02AX
Antacids, other combinations

Active Ingredients

Chemical substance
Description
Almagate

Almagate is an aluminium- and magnesium-containing antacid.

Almasilate

Almasilate is an antacid compound, consisting of a crystalline aluminum/magnesium silicate polymer. It guffers gastric acid by binding hydrogen ions within the polymer.

Aluminium glycinate
Aluminium hydroxide

Aluminium hydroxide is a slow-acting antacid. It is used to provide symptomatic relief in gastric hyperacidity. In addition, the antipeptic and demulcent activity of aluminium hydroxide helps to protect inflamed gastric mucosa against further irritation by gastric secretions.

Adsorbed aluminum phosphate
Calcium carbonate

Calcium carbonate releases, in a pH-dependent manner, calcium ions in the stomach. Calcium carbonate is widely used as antacid and extensively used as a dietary supplement.

Hydrotalcite

Hydrotalcite is a layered double hydroxide of general formula Mg6Al2CO3(OH)16·4(H2O), whose name is derived from its resemblance with talc and its high water content. The carbonate anions that lie between the structural layers are weakly bound, so hydrotalcite has anion exchange capabilities. Hydrotalcite is also used as an antacid.

Magaldrate

Magaldrate is a common antacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.

Magnesium carbonate

Magnesium carbonate, MgCO3 (archaic name magnesia alba), is an inorganic salt. The most common magnesium carbonate forms are the anhydrous salt called magnesite (MgCO3) and the di, tri, and pentahydrates known as barringtonite (MgCO3·2 H2O), nesquehonite (MgCO3·3 H2O), and lansfordite (MgCO3·5 H2O), respectively. The primary use of magnesium carbonate is the production of magnesium oxide by calcining.

Magnesium hydroxide

Magnesium hydroxide is practically insoluble in water and solution is not effected until the hydroxide reacts with hydrochloric acid in the stomach to form magnesium chloride. Its neutralising action is almost equal to that of sodium bicarbonate. When the dose is in excess of that required to neutralise the acid the intragastric pH may reach pH 8 or 9. Acid rebound following magnesium hydroxide is clinically insignificant. Magnesium hydroxide has an indirect cathartic effect resulting from water retention in the intestinal lumen.

Magnesium oxide

Magnesium oxide (MgO), or magnesia, is an empirical formula of MgO and consists of a lattice of Mg2+ ions and O2− ions held together by ionic bonding.

Magnesium silicate

Monographs

Monograph
Type
Country
ALU-CAP Capsules
MPI, EU: SmPC
UK
ALUTRIL FORTE Chewable tablet
MPI, EU: SmPC
CY
MILK OF MAGNESIA Oral Suspension
MPI, EU: SmPC
UK