ATC Group: A03AA Synthetic anticholinergics, esters with tertiary amino group

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of A03AA in the ATC hierarchy

Level Code Title
1 A Alimentary tract and metabolism
2 A03 Drugs for functional gastrointestinal disorders
3 A03A DRUGS FOR FUNCTIONAL BOWEL DISORDERS
4 A03AA Synthetic anticholinergics, esters with tertiary amino group

Group A03AA contents

Code Title
A03AA01 Oxyphencyclimine
A03AA03 Camylofin
A03AA04 Mebeverine
A03AA05 Trimebutine
A03AA06 Rociverine
A03AA07 Dicycloverine
A03AA08 Dihexyverine
A03AA09 Difemerine
A03AA30 Piperidolate

Active ingredients in A03AA

Active Ingredient Description
Dicycloverine

Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract and is used for the treatment of patients with functional bowel/irritable bowel syndrome. It can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, cause drowsiness, dilate the pupils, increase heart rate, and depress motor function.

Mebeverine

Mebeverine is a musculotropic antispasmodic with a direct action on the smooth muscle of the gastrointestinal tract, relieving spasm without affecting normal gut motility.

Oxyphencyclimine
Piperidolate
Trimebutine

Trimebutine maleate is a noncompetitive spasmolytic agent. It possesses moderate opiate receptor affinity and has a marked antiserotonin activity especially on ‘M’ receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig taenia coli and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.

Related product monographs

Title Information Source Document Type  
AUROBEVERINE Modified-release capsule, hard Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
BENTYL Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR
COLOFAC Coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
COLOFAC Modified release capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DUSPATALIN Modified release capsule, hard Υπουργείο Υγείας (CY) MPI, EU: SmPC