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ATC Group: A03AA Synthetic anticholinergics, esters with tertiary amino group

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A03
Drugs for functional gastrointestinal disorders
3
A03A
DRUGS FOR FUNCTIONAL BOWEL DISORDERS
4
A03AA
Synthetic anticholinergics, esters with tertiary amino group

Contents

Code
Title
A03AA01
Oxyphencyclimine
A03AA03
Camylofin
A03AA04
Mebeverine
A03AA05
Trimebutine
A03AA06
Rociverine
A03AA07
Dicycloverine
A03AA08
Dihexyverine
A03AA09
Difemerine
A03AA30
Piperidolate

Active Ingredients

Chemical substance
Description
Dicycloverine

Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract and is used for the treatment of patients with functional bowel/irritable bowel syndrome. It can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, cause drowsiness, dilate the pupils, increase heart rate, and depress motor function.

Mebeverine

Mebeverine is a musculotropic antispasmodic with a direct action on the smooth muscle of the gastrointestinal tract, relieving spasm without affecting normal gut motility.

Trimebutine

Trimebutine maleate is a noncompetitive spasmolytic agent. It possesses moderate opiate receptor affinity and has a marked antiserotonin activity especially on ‘M’ receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig taenia coli and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.