Leading the way to safer medication
 Crosscheck  Recommender

ATC Group: A04AA04 Dolasetron

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A04
Antiemetics and antinauseants
3
A04A
Antiemetics and antinauseants
4
A04AA
Serotonin (5HT3) antagonists
5
A04AA04
Dolasetron

Active Ingredients

Chemical substance
Description
Dolasetron

Dolasetron and its active metabolite, hydrodolasetron (MDL 74,156), are selective serotonin 5-HT3 receptor antagonists not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors. The serotonin 5-HT3 receptors are located on the nerve terminals of the vagus in the periphery and centrally in the chemoreceptor trigger zone of the area postrema.