ATC Group: A04AA04 Dolasetron

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of A04AA04 in the ATC hierarchy

Level
Code
Title
1
Alimentary tract and metabolism
2
Antiemetics and antinauseants
3
Antiemetics and antinauseants
4
Serotonin (5HT3) antagonists
5
A04AA04
Dolasetron

Defined daily dose

The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.

Route
Amount
ORAL - Oral
0.2 g
PAREN - Parenteral
0.1 g

Active ingredients in A04AA04

Active Ingredient
Description

Dolasetron and its active metabolite, hydrodolasetron (MDL 74,156), are selective serotonin 5-HT3 receptor antagonists not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors. The serotonin 5-HT3 receptors are located on the nerve terminals of the vagus in the periphery and centrally in the chemoreceptor trigger zone of the area postrema.

Medicines in this ATC group

Drug
Countries

United States