Chemical formula: C₁₉H₂₀N₂O₃ Molecular mass: 324.38 g/mol PubChem compound: 3033818
Dolasetron and its active metabolite, hydrodolasetron (MDL 74,156), are selective serotonin 5-HT3 receptor antagonists not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors. The serotonin 5-HT3 receptors are located on the nerve terminals of the vagus in the periphery and centrally in the chemoreceptor trigger zone of the area postrema.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A04AA04 | Dolasetron | A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AA Serotonin (5HT3) antagonists |
Dolasetron is an active ingredient of these brands:
United States (US)
Mexico (MX)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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