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ATC Group: A07EC03 Olsalazine

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
  English
Olsalazine

Hierarchical Position

Active Ingredients

Chemical substance
Description

Olsalazine is bioconverted to 5-aminosalicylic acid (5-ASA), which has anti-inflammatory activity in ulcerative colitis. The conversion of olsalazine to mesalamine (5-ASA) in the colon is similar to that of sulfasalazine, which is converted into sulfapyridine and mesalamine. The mechanism of action of mesalamine (and sulfasalazine) is unknown, but appears to be topical rather than systemic.

Monographs

Monograph
Type
Country
MPI, US: SPL/Old
US