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ATC Group: A10BG03 Pioglitazone

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A10
Drugs used in diabetes
3
A10B
Blood glucose lowering drugs, excl. insulins
4
A10BG
Thiazolidinediones
5
A10BG03
Pioglitazone

Active Ingredients

Chemical substance
Description
Pioglitazone

Pioglitazone effects may be mediated by a reduction of insulin resistance. Pioglitazone appears to act via activation of specific nuclear receptors (peroxisome proliferator activated receptor gamma) leading to increased insulin sensitivity of liver, fat and skeletal muscle cells in animals. Treatment with pioglitazone has been shown to reduce hepatic glucose output and to increase peripheral glucose disposal in the case of insulin resistance.

Monographs

Monograph
Type
Country
ACTOS Tablet
MPI, US: SPL/PLR
US
PIOGLITAZONE ACCORD Tablet
MPI, EU: SmPC
UK