ATC Group: A10BG Thiazolidinediones

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of A10BG in the ATC hierarchy

Level Code Title
1 A Alimentary tract and metabolism
2 A10 Drugs used in diabetes
3 A10B Blood glucose lowering drugs, excl. insulins
4 A10BG Thiazolidinediones

Group A10BG contents

Code Title
A10BG01 Troglitazone
A10BG02 Rosiglitazone
A10BG03 Pioglitazone

Active ingredients in A10BG

Active Ingredient Description

Pioglitazone effects may be mediated by a reduction of insulin resistance. Pioglitazone appears to act via activation of specific nuclear receptors (peroxisome proliferator activated receptor gamma) leading to increased insulin sensitivity of liver, fat and skeletal muscle cells in animals. Treatment with pioglitazone has been shown to reduce hepatic glucose output and to increase peripheral glucose disposal in the case of insulin resistance.


Rosiglitazone is a selective agonist at the PPARγ (peroxisomal proliferator activated receptor gamma) nuclear receptor and is a member of the thiazolidinedione class of anti-diabetic agents. It reduces glycaemia by reducing insulin resistance at adipose tissue, skeletal muscle and liver.

Related product monographs

Title Information Source Document Type  
ACTOS Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
ACTOS Tablet European Medicines Agency (EU) MPI, EU: SmPC
AVANDIA Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
AVANDIA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
GLUSTIN Tablet European Medicines Agency (EU) MPI, EU: SmPC
PIOGLITAZONE ACCORD Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC