Rosiglitazone
Chemical formula: C₁₈H₁₉N₃O₃S Molecular mass: 357.427 g/mol PubChem compound: 77999
Active ingredient description
Rosiglitazone is a selective agonist at the PPARγ (peroxisomal proliferator activated receptor gamma) nuclear receptor and is a member of the thiazolidinedione class of anti-diabetic agents. It reduces glycaemia by reducing insulin resistance at adipose tissue, skeletal muscle and liver.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| A10BG02 | Rosiglitazone | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BG Thiazolidinediones |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| AVANDIA Film-coated tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| AVANDIA Film-coated tablet | MPI, EU: SmPC | European Medicines Agency (EU) |
Medicines
Rosiglitazone is an active ingredient of these brands:
Lithuania (LT)Mexico (MX)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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